Hedgehog signaling is required for many aspects of development in vertebrates and invertebrates.Misregulation of the Hedgehog pathway causes developmental abnormalities and has been implicated in certain types of cancer.Large-scale genetic screens in zebrafish have identified a group of mutations, termed you-class mutations, that share common defec
Organized crime is often associated with traditional criminal groups, such as the mafia or outlaw coastal clouds vanilla custard motorcycle gangs; however, new research suggests that cybercrime is emerging as a new branch of organized crime.This paper is focused on the changing nature of organized crime and the factors that influence this shift, pa
Qiang Cai, Baowei Ji, Zhiyang Li, Wenju Wang, Junhui Liu, Zhibiao Chen Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, People’s Republic of ChinaCorrespondence: Qiang Cai; Baowei Ji Tel +86-15072358160; +86-18062565552Email cqno@sina.com; jbw2002@whu.edu.cnBackground: Traditionally, cerebral arterioveno
Introduction: Several studies have shown an association between homicide and sexual chromosomal abnormalities, but data are still lacking regarding Klinefelter syndrome.Methods: We retrospectively reviewed two cases of homicide perpetrators ej10 who were both diagnosed with Klinefelter syndrome on the basis of a karyotype analysis.A neurocognitive
Abstract Background An organic extract of the recreational herb khat (Catha edulis Forsk.) triggers cell death in various leukemia cell lines in vitro.The chemotherapeutics camptothecin, a plant alkaloid topoisomerase I inhibitor, was tested side-by-side with khat in a panel of acute myeloid leukemia cell lines to elucidate mechanisms of toxicity.R